アスビオファーマ株式会社：会社情報：研究論文

これまでに弊社の研究員が発表した研究論文（抜粋）の一覧表です。

件名	投稿雑誌名等	発表者
A claudin-4 modulator enhances the mucosal absorption of a biologically active peptide.	Biochem Pharmacol. 2010 May 15; 79(10): 1437-1444.	Uchida H, Kondoh M, Hanada T, Takahashi A, Hamakubo T, Yagi K.
A non-genetic method for purifying stem cell-derived cardiomyocytes.	Nat Methods. 2009 (in print)	Hattori F, Chen H, Yamashita H, Tohyama S, Satoh Y, Yuasa S, Li W, Yamakawa H, Tanaka T, Onitsuka T, Shimoji K, Ohno Y, Egashira T, Kaneda R, Murata M, Hidaka K, Morisaki T, Sasaki E, Suzuki T, Sano M, Makino S, Oikawa S, Fukuda K
Evaluation of ovotoxicity induced by 7, 12-dimethylbenz[a] anthracene and its 3,4-diol metabolite utilizing a rat in vitro ovarian culture system.	Toxicol Appl Pharmacol. 2009 Feb 1; 234(3): 361-369. Epub 2008 Nov 5.	Igawa Y, Keating AF, Rajapaksa KS, Sipes IG, Hoyer PB.
Upregulation of soluble vascular endothelial growth factor receptor type 1 by endogenous prostacyclin inhibitor coupling factor 6 in vascular endothelial cells: a role of acidosis-induced c-Src activation.	Hypertens Res. Mar 2009; 32(3): 182-187.	Echizen T, Osanai T, Ashitate T, Yokoyama H, Shibutani S, Tanaka M, Tomita H, Magota K, and Okumura K
Coupling factor 6 enhances Src-mediated responsiveness to angiotensin II in resistance arterioles and cells	Cardiovasc Res. Mar 2009; 81: 780-787	Osanai T, Tomita H, Kushibiki M, Yamada M, Tanaka M, Ashitate T, Echizen T, Katoh C, Magota K, and Okumura K
Oral administration of chymase inhibitor improves dermatitis in NC/Nga mice.	J Invest Dermatol. 2007; 127(4): 971-973.	Watanabe N, Tomimori Y, Terakawa M, Ishiwata K, Wada A, Muto T, Tanaka T, Maruoka H, Nagahira K, Nakatsuka T, Fukuda Y.
N-acetyl-seryl-aspartyllysyl-proline ameliorates the progression of renal dysfunction and fibrosis in WKY rats with established anti-glomerular basement membrane nephritis.	J Am Soc Nephrol. 2006; 17(3): 674-685.	Omata M, Taniguchi H, Koya D, Kanasaki K, Sho R, Kato Y, Kojima R, Haneda M, Inomata N.
Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells.	Nat Biotechnol. 2005; 23(5): 607-611.	Yuasa S, Itabashi Y, Koshimizu U, Tanaka T, Sugimura K, Kinoshita M, Hattori F, Fukami S, Shimazaki T, Ogawa S, Okano H, Fukuda K.
Semisynthesis of Human Ghrelin: Condensation of a Boc-Protected Recombinant Peptide with a Synthetic O-Acylated Fragment	Biopolymers. 2005; 79: 238-247.	Makino T, Matsumoto M, Suzuki Y, Kitajima Y, Yamamoto K, Kuramoto M, Minamitake Y, Kangawa K, Yabuta M
Periostin as a novel factor responsible for ventricular dilation.	Circulation. 2004; 110(13): 1806-1813.	Katsuragi N, Morishita R, Nakamura N, Ochiai T, Taniyama Y, Hasegawa Y, Kawashima K, Kaneda Y, Ogihara T, Sugimura K.
Upregulation of ghrelin expression in cachectic nude mice bearing human melanoma cells.	Metabolism. 2004; 53: 84-88.	Hanada T, Toshinai K, Date Y, Kajimura N, Tsukada T, Hayashi Y, Kangawa K, Nakazato M.
Central actions of neuromedin U via corticotropin-releasing hormone.	Biochem Biophys Res Commun. 2003; 311: 954-958.	Hanada T, Date Y, Shimbara T, Sakihara S, Murakami N, Hayashi Y, Kanai Y, Suda T, Kangawa K, Nakazato M.
Altered expression of amyloid precursors proteins after traumatic brain injury in rats: in situ hybridization and immunohistochemical study.	J Neurotrauma. 2000; 17(2): 123-134.	Masumura M, Hata R, Uramoto H, Murayama N, Ohno T, Sawada T.
Discovery of (2S)-1-(4-amino-2,3,5-trimethylphenoxy)-3-[4-[4-(4-fluorobenzyl)phenyl]-1-piperazinyl]-2-propanol dimethanesulfonate (SUN N8075): a dual Na(+) and Ca(2+) channel blocker with antioxidant activity.	J Med Chem. 2000; 43(18): 3372-3376.	Annoura H, Nakanishi K, Toba T, Takemoto N, Imajo S, Miyajima A, Tamura-Horikawa Y, Tamura S.
5,6-Cis-penems: broad-spectrum anti-methicillin-resistant Staphylococcus aureus betalactam antibiotics.	J Med Chem. 1997; 40(14): 2126-2132.	Ishiguro M, Tanaka R, Namikawa K, Nasu T, Inoue H, Nakatsuka T, Oyama Y, Imajo S.
A specific heterotypic cell adhesion activity between members of carcinoembryonic antigen family, W272 and NCA, is mediated by N-domains.	J Biol Chem. 1991; 266(13): 7995-8001.	Oikawa S, Inuzuka C, Kuroki M, Arakawa F, Matsuoka Y, Kosaki G, Nakazato H.
Identification of membrane anchoring site of human renal dipeptidase and construction and expression of a cDNA for its secretory form.	J Biol Chem. 1990; 265(25): 15341-15345.	Adachi H, Katayama T, Inuzuka C, Oikawa S, Tsujimoto M, Nakazato H.
Synergistic in vitro and in vivo anti-tumor effect of daunomycinanti-96-kDa melanoma-associated antigen monoclonal antibody CL 207 conjugate and recombinant IFN-gamma.	J Immunol. 1988; 141(4): 1410-1417.	Matsui M, Nakanishi T, Noguchi T, Ferrone S.
New antiarrhythmic agents. N-aryl-8-pyrrolizidinealkanamides.	J Med Chem. 1985 Jun; 28(6): 714-717.	Miyano S, Sumoto K, Satoh F, Shima K, Hayashimatsu M, Morita M, Aisaka K, Noguchi T.
Cloning and sequence analysis of cDNA encoding a precursor for human atrial natriuretic polypeptide.	Nature. 1984; 309(5970): 724-726.	Oikawa S, Imai M, Ueno A, Tanaka S, Noguchi T, Nakazato H, Kangawa K, Fukuda A, Matsuo H.
Identification of rat gamma atrial natriuretic polypeptide and characterization of the cDNA encoding its precursor.	Nature. 1984; 312(5990): 152-155.	Kangawa K, Tawaragi Y, Oikawa S, Mizuno A, Sakuragawa Y, Nakazato H, Fukuda A, Minamino N, Matsuo H.